Publications
Sala G, Traini S, D’Egidio M, Vianale G, Rossi C, Piccolo E, Lattanzio R, Piantelli M, Tinari N, Natali PG, Muraro R, Iacobelli S
Oncogene 8:1275-86 (2012)
Piccolo E, Tinari N, Semeraro D, Traini S, Fichera I, Cumashi A, La Sorda R, Spinella F, Bagnato A, Lattanzio R, D’Egidio M, Di Risio A, Stampolidis P, Piantelli M, Natoli C, Ullrich A, Iacobelli S.
J Mol Med 91:83-94 (2013)
Sara Traini, Enza Piccolo, Nicola Tinari, Cosmo Rossi, Rossana La Sorda, Francesca Spinella, Anna Bagnato, Rossano Lattanzio, Maurizia D’Egidio, Annalisa Di Risio, Federica Tomao, Antonino Grassadonia,Mauro Piantelli, Clara Natoli and Stefano Iacobelli.
Mol Cancer Ther. 3: 916-925 (2014)
Galit Yahalom, Daria Weiss, Ilya Novikov, Therese B. Bevers, Laszlo G. Radvanyi, Mei Liu, Benjamin Piura, Stefano Iacobelli, Maria T. Sandri, Enrico Cassano, Tanir M. Allweis,Arie Bitterman, Pnina Engelman, Luis M. Vence and Marvin M. Rosenberg
Biomarkers in Cancer 5: 71-80 (2013)
Pavlos Stampolidis, Axel Ullrich, and Stefano Iacobelli
Oncogene 34:39-52 (2015)
EV20, a Novel Anti ErbB-3 Humanized Antibody, Promotes ErbB-3 Down-Regulation and Inhibits Tumor Growth In Vivo.
Sala G, Rapposelli IG, Ghasemi R, Piccolo E, Traini S, Capone E, Rossi C, Pelliccia A, Di Risio A, D?Egidio M, Tinari N, Muraro R, Iacobelli S
Transl Oncol 6: 676-84 ( 2013)
Ghasemi R, Rapposelli IG, Capone E, Rossi C, Lattanzio R, Piantelli M, Sala G. Iacobelli S.
Oncogenesis 18;3:e117 (2014).
Lattanzio R, Ghasemi R, Brancati F, Sorda RL, Tinari N, Perracchio L, Iacobelli S, Mottolese M, Natali P, Piantelli M
Oncogenesis (2014) S3:e118. doi: 10.1038.
Momeny M, Saunus JM, Marturana F, McCart Reed AE, Black D, Sala G, Iacobelli S, Holland JD, Birchmeier W, Yu D, Da Silva L, Simpson PT, Khanna K, Chenevix-Trench G and Lakhani SR.
Oncotarget (2015);6:3932-46
Pramudita R Prasetyanti, Emily Capone, Daniela Barcaroli, Daniela D’Agostino, Silvia Volpe, Antonina Benfante, Sander van Hooff, Valentina Iacobelli, Cosmo Rossi, Stefano Iacobelli, Jan Paul Medema, Vincenzo De Laurenzi and Gianluca Sala
Oncotarget 6:16902-11 (2015).
Prognostic relevance of LGALS3BP in human colorectal carcinoma
Enza Piccolo, Nicola Tinari, Domenica D’Addario, Cosmo Rossi, Valentina Iacobelli, Rossana La Sorda,
Rossano Lattanzio, Maurizia D’Egidio, Annalisa Di Risio, Mauro Piantelli1, Pier Giorgio Natali and Stefano Iacobelli
J Transl Med (2015) 13:248
HER-3: hub for escape mechanisms
Emily Capone, Pramudita R Prasetyanti, and Gianluca Sala
AGING, November 2015, Vol. 7 No.11
Rossano Lattanzio, Serena Veschi, Gitana Maria Aceto, Maria Cristina Curia, Alessandro Cama, Laura De Lellis, Fabiana Fantini, Domenico Angelucci, Stefano Iacobelli, Mauro Piantelli, and Pasquale Battista
Oncol Lett 12: 453-458, 2016
Gabriele Corda, Gianluca Sala, Rossano Lattanzio, Manuela Iezzi, Michele Sallese, Giorgia Fragassi, Alessia Lamolinara, Hasan Mirza, Daniela Barcaroli, Sibylle Ermler, Elisabete Silva, Hemad Yasaei, Robert F Newbold, Paola Vagnarelli, Marcella Mottolese, Pier Giorgio Natali, Letizia Perracchio, Jelmar Quist, Anita Grigoriadis, Pierfrancesco Marra, Andrew N Tutt, Mauro Piantelli, Stefano Iacobelli, Vincenzo De Laurenzi and Arturo Sala
J Pathol 2017; 241: 350–361
Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma
Emily Capone , Enza Piccolo , Imma Fichera , Paolo Ciufici , Daniela Barcaroli , Arturo Sala , Stefano Iacobelli Vincenzo De Laurenzi , Valentina Iacobelli , Gianluca Sala
Oncotarget. 2017; 8:60368-60377
Emily Capone, Francesco Giansanti, Sara Ponziani, Alessia Lamolinara, Manuela Iezzi, Annamaria Cimini, Francesco Angelucci, Rossana La Sorda, Vincenzo De Laurenzi, Pier Giorgio Natali, Rodolfo Ippoliti, Gianluca Sala
Oncotarget https://doi.org/10.18632/oncotarget.20728
Emily Capone, Alessia Lamolinara, Daniela D’Agostino, Cosmo Rossi, Vincenzo De Laurenzi, Manuela Iezzi, Stefano Iacobelli and Gianluca Sala
J Control Release. 2018 Mar 14;277:48-56
Secreted Gal-3 BP is a novel promising target for noninternalizing Antibody-Drug Conjugates
Francesco Giansanti, Emily Capone, Sara Ponziani, Enza Piccolo, Roberta Gentile, Alessia Lamolinara, Antonella Di Campli, Michele Sallese, Valentina Iacobelli, Annamaria Cimini, Vincenzo De Laurenzi, Rossano Lattanzio, Mauro Piantelli, Rodolfo Ippoliti, Gianluca Sala, Stefano Iacobelli
J Control Release. 2018 Dec 13;294:176-184
HER3 targeting with an antibody-drug conjugate bypasses resistance to anti-HER2 therapies.
Lucía Gandullo-Sánchez , Emily Capone , Alberto Ocaña , Stefano Iacobelli , Gianluca Sala and Atanasio Pandiella
EMBO Mol Med. 2020 Apr 24:e11498. doi
Sara Ponziani, Giulia Di Vittorio, Giuseppina Pitari, Anna Maria Cimini, Matteo Ardini, Roberta Gentile, Stefano Iacobelli, Gianluca Sala, Emily Capone, David J. Flavell, Rodolfo Ippoliti, Francesco Giansanti
Int J Mol Sci. 2020 Aug; 21(15): 5510
Targeting vesicular LGALS3BP by an antibody-drug conjugate as novel therapeutic strategy for neuroblastoma
Emily Capone, Alessia Lamolinara, Fabio Pastorino, Roberta Gentile, Sara Ponziani, Giulia Di Vittorio, Daniela D’Agostino, Sandra Bibbò, Cosmo Rossi, Enza Piccolo, Valentina Iacobelli, Rossano Lattanzio, Valeria Panella, Michele Sallese, Vincenzo De Laurenzi, Francesco Giansanti, Arturo Sala, Manuela Iezzi, Mirco Ponzoni, Rodolfo Ippoliti, Stefano Iacobelli, Gianluca Sala
Cancers (Basel). 2020 Oct 15;12(10):2989
Anlal Bioanal Chem. 2020 Nov;412(27):7659-7667
- Daniela D’Agostino, Roberta Gentile, Sara Ponziani, Giulia Di Vittorio, Francesco Dituri, Gianluigi Giannelli, Cosmo Rossi, Liberato Marzullo, Francesco Giansanti, Vincenzo De Laurenzi, Stefano Iacobelli, Rodolfo Ippoliti, Emily Capone, Gianluca Sala
Oncol Rep 45, 776-785 (2021)
EV20/NMS-P945, a Novel Thienoindole Based Antibody-Drug Conjugate Targeting HER-3 for Solid Tumors.
Emily Capone, Rossano Lattanzio, Fabio Gasbarri, Paolo Orsini, Valentina Iacobelli, Vincenzo De Laurenzi, Piergiorgio Natali, Barbara Valsasina, Stefano Iacobelli and Gianluca Sala
Phrmaceutics 2, 483 (2021)
Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target.
Emily Capone, Stefano Iacobelli, Gianluca Sala
J Transì Med 19: 405 (2021)
Valentina Gallo, Team ISERC, Roberta Gentile, Giovanni Antonini, Stefano Iacobelli
Clin Exp Med. 2022 Jan 25:1-5.
Jose Vicencio, Rachel Evans, Ryan Green, Zhengwen An, Jinhai Deng, Conor Treacy, Rami Mustapha, James Monypenny, Cristobal Costoya, Katherine Lawler, Kenrick Ng, Karen De Souza, Oana Coban, Valenti Gomez, Joanne Clancy, Shih-Hsin Chen, Avigayil Chalk, Felix Wong, Peter Gordon, Courtney Savage, Camila Gomes, Teng Pan, Giovanna Alfano, Luigi Dolcetti, Julie Chan, Fabian Florez-Borja, Paul Barber, Gregory Weitsman, Dominika Sosnowska, Emily Capone, Stefano Iacobelli, Daniel Hochhauser, John Hartley, Maddy Parsons, James Arnold, Simon Ameer-Beg, Sergio Quezada, Yosef Yarden, Gianluca Sala, and Tony Ng
Cell Death & Dis (2022); 3:274
Gal-3BP in Viral Infections: An Emerging Role in Severe Acute Respiratory Syndrome Coronavirus 2
Int J Mol Sci. 2022 Jul; 23(13): 7314
Mendes-Frias, Valentina Gallo, Valentina Iacobelli, Roberta Gentile, Giovanni Antonini, Ricardo Silvestre, Stefano Iacobelli
Sci Rep 2022, 12: 17047
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans
Vicencio JM, Evans R, Green R, An Z, Deng J, Treacy C, Mustapha R, Monypenny J, Costoya C, Lawler K, Ng K, De-Souza K, Coban O, Gomez V, Clancy J, Chen SH, Chalk A, Wong F, Gordon P, Savage C, Gomes C, Pan T, Alfano G, Dolcetti L, Chan JNE, Flores-Borja F, Barber PR, Weitsman G, Sosnowska D, Capone E, Iacobelli S, Hochhauser D, Hartley JA, Parsons M, Arnold JN, Ameer-Beg S, Quezada SA, Yarden Y, Sala G, Ng T
Cell Death Dis. 2022 Mar 28;13(3):274.
Beatrice Dufrusine, Emily Capone, Sara Ponziani, Rossano Lattanzio, Paola Lanuti, Francesco Giansanti, Vincenzo De Laurenzi; Stefano Iacobelli; Rodolfo Ippoliti, Annunziato Mangiola, Gianluca Trevisi and Gianluca Sala
Mol Oncol 2023 Aug;17(8):1460-1473. doi: 10.1002/1878-0261.13453.
Visualizing Galectin-3 Binding Protein Expression with ImmunoPET
Outi Keinänen, Samantha M. Sarrett, Samantha Delaney, Cindy Rodriguez, Eric J. Dayts, Emily Capone, Frederic Sauniere, Rodolfo Ippoliti, Gianluca Sala, Stefano Iacobelli, Brian M Zeglis
Mol Pharm 2023;20(6):3241-3248.
Gianluca Sala, Emily Capone, Thordur Tryggvason, Ilaria Cela, Beatrice Dufrusine, Morena Pinti, Francesco Del Pizzo, Helga Sigrún Gunnarsdóttir, Tommaso Grottola, Vincenzo De Laurenzi, Stefano Iacobelli, and Rossano Lattanzio
Cell Death Discovery (2023) 9:400.
Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain
Sirko S, Schichor C, Della Vecchia, Metzger F, Sonsalla G, , Bürkle M, Kalpazidou S, Ninkovic J, Masserdotti G, Sauniere JF, Iacobelli V, Iacobelli S, Delbridge C, Hauck SM, Tonn JC and Götz M
Nat Med 2023 12:3149-3161; doi: 10.1038/s41591-023-02644-6.
Capone E, Perrotti N, Cela R, Togni L, Rubini C, Caponio VCA, Lo Muzio L, Giansanti F, Ippoliti R, Iacobelli S, Spardy N and Gianluca Sala G
Oral Oncol (2024) 123, 106635