TRK A is the high affinity catalytic receptor for the neurotrophin Nerve Growth Factor. Besides mediating neuronal differentiation and survival, it plays a role in the tumorigenesis of nonneural tumors, primarily carcinomas.
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BACKGROUND
TRK-A is the high affinity catalytic receptor for the neurotrophin Nerve Growth Factor. Besides mediating neuronal differentiation and survival, it plays a role in the tumorigenesis of non neural tumors, primarily carcinomas.
PRODUCT
1. Each vial contains the indicated amount of IgG (caprylic acid purified) in 0.1% gelatine and 0.05% NaN3.
2. Unpurified reagent is provided at the indicated amounts with 0.1% NaN3.
Centrifuge the vial prior to use.
SPECIFICITY
The murine monoclonal antibody MP-AA-6 (IgG-2a), has been generated using as immunogen NIH-3T3 cells transfected with the full length human molecule. It recognizes the receptor with an affinity of 2x10- 11 M.
STORAGE
Store frozen, avoid repeated freezing-thawing. Stable for 2 yrs.
SHIPPING CONDITIONS
Room temperature.
RESEARCH USE
This antibody is for laboratory research use only, not for human or in-vivo use.
APPLICATIONS
Flow Cytometry, 5-10 µg/ml.
Immunohistochemistry (fluourescence, enzymatic), Acetone fixed cryostat sections or cytospins (20 µg/ml).
Immunoprecipitation, 5-10 µg, using rabbit anti-mouse Ig and protein ASepharose.
Last updated: 21/07/2011 10:10
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