TRK A receptor

TRK A is the high affinity catalytic receptor for the neurotrophin Nerve Growth Factor. Besides mediating neuronal differentiation and survival, it plays a role in the tumorigenesis of nonneural tumors, primarily carcinomas.

 

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Antibody to Catalogue NumberDATA
SHEET
Clone   Unit Size       Antibody form  Host animalIsotype    Price (€)    Order

  Human
TRK-A receptor

MP-AA-06.1
H-10
150 µg Caprylic ac.
purified
Mouse monoclonal  IgG2a 300,00 TRK-A

 

MP-AA-06.2   H-10
 50 µl Unpurified reagent  Mouse monoclonal  IgG2a  200,00 TRK-A
  MP-AA-06.3     H-10 200 µl   Unpurified reagent Mouse monoclonal   IgG2a   560,00 TRK-A
 

 

 

Datasheet preview

BACKGROUND

TRK-A is the high affinity catalytic receptor for the neurotrophin Nerve Growth Factor. Besides mediating neuronal differentiation and survival, it plays a role in the tumorigenesis of non neural tumors, primarily carcinomas.


PRODUCT

1. Each vial contains the indicated amount of IgG (caprylic acid purified) in 0.1% gelatine and 0.05% NaN3.

2. Unpurified reagent is provided at the indicated amounts with 0.1% NaN3.

Centrifuge the vial prior to use.


SPECIFICITY

The murine monoclonal antibody MP-AA-6 (IgG-2a), has been generated using as immunogen NIH-3T3 cells transfected with the full length human molecule. It recognizes the receptor with an affinity of 2x10- 11 M.


STORAGE

Store frozen, avoid repeated freezing-thawing. Stable for 2 yrs.


SHIPPING CONDITIONS

Room temperature.


RESEARCH USE

This antibody is for laboratory research use only, not for human or in-vivo use.


APPLICATIONS

Flow Cytometry,  5-10 µg/ml.

Immunohistochemistry (fluourescence, enzymatic),  Acetone fixed cryostat sections or cytospins (20 µg/ml).

Immunoprecipitation,   5-10 µg, using rabbit anti-mouse Ig and protein ASepharose.

 

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Last updated: 21/07/2011 10:10

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