The company is focused on the discovery, development and commercialization of monoclonal antibodies
Human Tyrosinase
The copper containing enzyme tyrosinase, essential to pigmentation in mammals, is specifically synthesized by epithelial and mucosal melanocytes, pigmented epithelium of the ciliary body and retina.
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| Antibody to | Catalogue Number | DATA SHEET | Clone | Unit Size | Antibody form | Host animal | Isotype | Price (€) | Order |
|---|---|---|---|---|---|---|---|---|---|
| Human Tyrosinase |
MP-AA-04.1 |  |
2G10b | 150 µg | Caprylic ac. purified |
Mouse monoclonal | IgG1 | 300,00 |  |
| MP-AA-04.2 | |
2G10b | 50 µl | Unpurified reagent | Mouse monoclonal | IgG1 | 200,00 | |
|
| MP-AA-04.3 | |
2G10b | 200 µl | Unpurified reagent | Mouse monoclonal | IgG1 |
560,00 |
|
Datasheet preview
BACKGROUND
The copper containing enzyme tyrosinase, essential to pigmentation in mammals, is specifically synthesized by epithelial and mucosal melanocytes, pigmented epithelium of the ciliary body and retina. The mature form of the enzyme, named T4, is a single-chain glycoprotein of 75KD localized in melanosomes.
PRODUCT
1. Each vial contains the indicated amount of IgG (caprylic acid purified) in 0.1% gelatine and 0.05% NaN3.
2. Unpurified reagent is provided at the indicated amounts with 0.1% NaN3.
Centrifuge the vial prior to use.
SPECIFICITY
The murine monoclonal antibody MP-AA-4 (IgG1) has been generated using a highly pigmented melanoma cell line as immunogen. It recognizes the human T4- tyrosinase. It does not cross reacts with the animal isoenzyme.
STORAGE
Store frozen, avoid repeated freezing and thawing. Stable for 2 yrs.
SHIPPING CONDITIONS
Room temperature.
RESEARCH USE
This antibody is for laboratory research use only, not for human or in-vivo use.
APPLICATIONS
Immunohistochemistry (fluorescence, enzymatic), Acetone fixed cryostat sections or cytospins (20 µg/ml).
Immunoprecipitation, 5 µg, using rabbit anti-mouse Ig and protein ASepharose.
Last updated: 21/07/2011 10:10
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